Found 4 hits for monomerid = 50217486 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1
(Homo sapiens (Human)) | BDBM50217486
((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)Show SMILES O=C(NC1CCC(CN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C30H37N5O3/c36-28-27(13-12-23(22-6-2-1-3-7-22)19-34(28)18-21-10-11-21)32-29(37)33-16-14-25(15-17-33)35-20-24-8-4-5-9-26(24)31-30(35)38/h1-9,21,23,25,27H,10-20H2,(H,31,38)(H,32,37) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes |
Bioorg Med Chem Lett 17: 4795-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D |
More data for this Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1
(Homo sapiens (Human)) | BDBM50217486
((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)Show SMILES O=C(NC1CCC(CN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C30H37N5O3/c36-28-27(13-12-23(22-6-2-1-3-7-22)19-34(28)18-21-10-11-21)32-29(37)33-16-14-25(15-17-33)35-20-24-8-4-5-9-26(24)31-30(35)38/h1-9,21,23,25,27H,10-20H2,(H,31,38)(H,32,37) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 695 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes |
Bioorg Med Chem Lett 17: 4795-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D |
More data for this Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1
(Homo sapiens (Human)) | BDBM50217486
((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)Show SMILES O=C(NC1CCC(CN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C30H37N5O3/c36-28-27(13-12-23(22-6-2-1-3-7-22)19-34(28)18-21-10-11-21)32-29(37)33-16-14-25(15-17-33)35-20-24-8-4-5-9-26(24)31-30(35)38/h1-9,21,23,25,27H,10-20H2,(H,31,38)(H,32,37) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 778 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production |
Bioorg Med Chem Lett 17: 4795-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D |
More data for this Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1
(Homo sapiens (Human)) | BDBM50217486
((cis racemic)-N-(1-(cyclopropylmethyl)-2-oxo-6-phe...)Show SMILES O=C(NC1CCC(CN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C30H37N5O3/c36-28-27(13-12-23(22-6-2-1-3-7-22)19-34(28)18-21-10-11-21)32-29(37)33-16-14-25(15-17-33)35-20-24-8-4-5-9-26(24)31-30(35)38/h1-9,21,23,25,27H,10-20H2,(H,31,38)(H,32,37) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production |
Bioorg Med Chem Lett 17: 4795-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D |
More data for this Ligand-Target Pair | |