BDBM50217490 CHEMBL428547::N-((3R,7R)-1-(cyclopropylmethyl)-2-oxo-7-phenylazepan-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide

SMILES: O=C(N[C@@H]1CCC[C@@H](N(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O

InChI Key: InChIKey=PORPTQSGGWNOJX-KAYWLYCHSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217490 (CHEMBL428547 | N-((3R,7R)-1-(cyclopropylmethyl)-2-...) Show SMILES O=C(N[C@@H]1CCC[C@@H](N(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C30H37N5O3/c36-28-26(11-6-12-27(22-7-2-1-3-8-22)35(28)19-21-13-14-21)32-29(37)33-17-15-24(16-18-33)34-20-23-9-4-5-10-25(23)31-30(34)38/h1-5,7-10,21,24,26-27H,6,11-20H2,(H,31,38)(H,32,37)/t26-,27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	689	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217490 (CHEMBL428547 | N-((3R,7R)-1-(cyclopropylmethyl)-2-...) Show SMILES O=C(N[C@@H]1CCC[C@@H](N(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O Show InChI InChI=1S/C30H37N5O3/c36-28-26(11-6-12-27(22-7-2-1-3-8-22)35(28)19-21-13-14-21)32-29(37)33-17-15-24(16-18-33)34-20-23-9-4-5-10-25(23)31-30(34)38/h1-5,7-10,21,24,26-27H,6,11-20H2,(H,31,38)(H,32,37)/t26-,27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair