BDBM50217647 CHEMBL238154::N-(4-((4-amino-3-methylcyclohexyl)methyl)-2-methylcyclohexyl)-N-benzyl-4-(1H-indol-3-yl)butanamide

SMILES: CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N

InChI Key: InChIKey=IKLPEMFMSKFWMF-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50217647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 1 (Mus musculus)	BDBM50217647 (CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)m...) Show SMILES CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| Show InChI InChI=1S/C34H47N3O/c1-24-19-27(15-17-31(24)35)21-28-16-18-33(25(2)20-28)37(23-26-9-4-3-5-10-26)34(38)14-8-11-29-22-36-32-13-7-6-12-30(29)32/h3-7,9-10,12-13,22,24-25,27-28,31,33,36H,8,11,14-21,23,35H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50217647 (CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)m...) Show SMILES CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| Show InChI InChI=1S/C34H47N3O/c1-24-19-27(15-17-31(24)35)21-28-16-18-33(25(2)20-28)37(23-26-9-4-3-5-10-26)34(38)14-8-11-29-22-36-32-13-7-6-12-30(29)32/h3-7,9-10,12-13,22,24-25,27-28,31,33,36H,8,11,14-21,23,35H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50217647 (CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)m...) Show SMILES CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| Show InChI InChI=1S/C34H47N3O/c1-24-19-27(15-17-31(24)35)21-28-16-18-33(25(2)20-28)37(23-26-9-4-3-5-10-26)34(38)14-8-11-29-22-36-32-13-7-6-12-30(29)32/h3-7,9-10,12-13,22,24-25,27-28,31,33,36H,8,11,14-21,23,35H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50217647 (CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)m...) Show SMILES CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| Show InChI InChI=1S/C34H47N3O/c1-24-19-27(15-17-31(24)35)21-28-16-18-33(25(2)20-28)37(23-26-9-4-3-5-10-26)34(38)14-8-11-29-22-36-32-13-7-6-12-30(29)32/h3-7,9-10,12-13,22,24-25,27-28,31,33,36H,8,11,14-21,23,35H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50217647 (CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)m...) Show SMILES CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| Show InChI InChI=1S/C34H47N3O/c1-24-19-27(15-17-31(24)35)21-28-16-18-33(25(2)20-28)37(23-26-9-4-3-5-10-26)34(38)14-8-11-29-22-36-32-13-7-6-12-30(29)32/h3-7,9-10,12-13,22,24-25,27-28,31,33,36H,8,11,14-21,23,35H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50217647 (CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)m...) Show SMILES CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| Show InChI InChI=1S/C34H47N3O/c1-24-19-27(15-17-31(24)35)21-28-16-18-33(25(2)20-28)37(23-26-9-4-3-5-10-26)34(38)14-8-11-29-22-36-32-13-7-6-12-30(29)32/h3-7,9-10,12-13,22,24-25,27-28,31,33,36H,8,11,14-21,23,35H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair