BDBM50217795 3-(2-deoxy-beta-d-erythro-pentofuranosyl)-6-(phenylethynyl)-furo[2,3-d]pyrimidin-2(3H)-one::CHEMBL243988

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cc2cc(oc2nc1=O)C#Cc1ccccc1

InChI Key: InChIKey=BUJJMVXWPYEBGO-GVDBMIGSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine kinase (Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)	BDBM50217795 (3-(2-deoxy-beta-d-erythro-pentofuranosyl)-6-(pheny...) Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cc2cc(oc2nc1=O)C#Cc1ccccc1 Show InChI InChI=1S/C19H16N2O5/c22-11-16-15(23)9-17(26-16)21-10-13-8-14(25-18(13)20-19(21)24)7-6-12-4-2-1-3-5-12/h1-5,8,10,15-17,22-23H,9,11H2/t15-,16+,17+/m0/s1	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
Brigham Young University Curated by ChEMBL					Assay Description Inhibition of VZV thymidine kinase				J Med Chem 50: 3897-905 (2007) Article DOI: 10.1021/jm070210n BindingDB Entry DOI: 10.7270/Q2S75G19
					More data for this Ligand-Target Pair