BDBM50218210 2,2,2-trifluoro-1-(4-(piperidin-1-yl)piperidin-1-yl)ethanone::CHEMBL250968::Tyrosinase Inhibitor, 6

SMILES: FC(F)(F)C(=O)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=DQAGGGYIGDZVEV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50218210 (2,2,2-trifluoro-1-(4-(piperidin-1-yl)piperidin-1-y...) Show SMILES FC(F)(F)C(=O)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C12H19F3N2O/c13-12(14,15)11(18)17-8-4-10(5-9-17)16-6-2-1-3-7-16/h10H,1-9H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase				Eur J Med Chem 42: 1370-81 (2007) Article DOI: 10.1016/j.ejmech.2007.01.026 BindingDB Entry DOI: 10.7270/Q23R0TP1
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50218210 (2,2,2-trifluoro-1-(4-(piperidin-1-yl)piperidin-1-y...) Show SMILES FC(F)(F)C(=O)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C12H19F3N2O/c13-12(14,15)11(18)17-8-4-10(5-9-17)16-6-2-1-3-7-16/h10H,1-9H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	6.8	37
University of Karachi					Assay Description Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...				J Enzyme Inhib Med Chem 20: 401-7 (2005) Article DOI: 10.1080/14756360500179333 BindingDB Entry DOI: 10.7270/Q29G5KBN
					More data for this Ligand-Target Pair