BDBM50218211 1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl::CHEMBL399558::Tyrosinase Inhibitor, 4

SMILES: Cc1ccc(CN2CCC(CC2)N2CCCCC2)cc1

InChI Key: InChIKey=XJYLZLHTPACMIL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50218211 (1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl | CHEMBL3...) Show SMILES Cc1ccc(CN2CCC(CC2)N2CCCCC2)cc1 Show InChI InChI=1S/C18H28N2/c1-16-5-7-17(8-6-16)15-19-13-9-18(10-14-19)20-11-3-2-4-12-20/h5-8,18H,2-4,9-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase				Eur J Med Chem 42: 1370-81 (2007) Article DOI: 10.1016/j.ejmech.2007.01.026 BindingDB Entry DOI: 10.7270/Q23R0TP1
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50218211 (1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl | CHEMBL3...) Show SMILES Cc1ccc(CN2CCC(CC2)N2CCCCC2)cc1 Show InChI InChI=1S/C18H28N2/c1-16-5-7-17(8-6-16)15-19-13-9-18(10-14-19)20-11-3-2-4-12-20/h5-8,18H,2-4,9-15H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	6.8	37
University of Karachi					Assay Description Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...				J Enzyme Inhib Med Chem 20: 401-7 (2005) Article DOI: 10.1080/14756360500179333 BindingDB Entry DOI: 10.7270/Q29G5KBN
					More data for this Ligand-Target Pair