Found 4 hits for monomerid = 50218262 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50218262
(CHEMBL308158)Show SMILES FC(F)Oc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCCC1 Show InChI InChI=1S/C20H17Cl2F2N3O2/c21-15-9-25-10-16(22)13(15)7-17-12-5-6-18(29-20(23)24)19(14(12)8-26-27-17)28-11-3-1-2-4-11/h5-6,8-11,20H,1-4,7H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description Inhibition of rolipram binding to PDE4 from human neutrophils |
Bioorg Med Chem Lett 10: 2235-8 (2000)
BindingDB Entry DOI: 10.7270/Q2J105BG |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50218262
(CHEMBL308158)Show SMILES FC(F)Oc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCCC1 Show InChI InChI=1S/C20H17Cl2F2N3O2/c21-15-9-25-10-16(22)13(15)7-17-12-5-6-18(29-20(23)24)19(14(12)8-26-27-17)28-11-3-1-2-4-11/h5-6,8-11,20H,1-4,7H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description Inhibition of Phosphodiesterase 4 from human neutrophils |
Bioorg Med Chem Lett 10: 2235-8 (2000)
BindingDB Entry DOI: 10.7270/Q2J105BG |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50218262
(CHEMBL308158)Show SMILES FC(F)Oc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCCC1 Show InChI InChI=1S/C20H17Cl2F2N3O2/c21-15-9-25-10-16(22)13(15)7-17-12-5-6-18(29-20(23)24)19(14(12)8-26-27-17)28-11-3-1-2-4-11/h5-6,8-11,20H,1-4,7H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50218262
(CHEMBL308158)Show SMILES FC(F)Oc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCCC1 Show InChI InChI=1S/C20H17Cl2F2N3O2/c21-15-9-25-10-16(22)13(15)7-17-12-5-6-18(29-20(23)24)19(14(12)8-26-27-17)28-11-3-1-2-4-11/h5-6,8-11,20H,1-4,7H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description Inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this Ligand-Target Pair | |