BDBM50218266 CHEMBL303880

SMILES: COc1cc2cnnc(Cc3c(Cl)cncc3Cl)c2cc1OC1CCCC1

InChI Key: InChIKey=FJBUIEZNAFNOQA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50218266 (CHEMBL303880) Show SMILES COc1cc2cnnc(Cc3c(Cl)cncc3Cl)c2cc1OC1CCCC1 Show InChI InChI=1S/C20H19Cl2N3O2/c1-26-19-6-12-9-24-25-18(7-15-16(21)10-23-11-17(15)22)14(12)8-20(19)27-13-4-2-3-5-13/h6,8-11,13H,2-5,7H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50218266 (CHEMBL303880) Show SMILES COc1cc2cnnc(Cc3c(Cl)cncc3Cl)c2cc1OC1CCCC1 Show InChI InChI=1S/C20H19Cl2N3O2/c1-26-19-6-12-9-24-25-18(7-15-16(21)10-23-11-17(15)22)14(12)8-20(19)27-13-4-2-3-5-13/h6,8-11,13H,2-5,7H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 4 from human neutrophils				Bioorg Med Chem Lett 10: 2235-8 (2000) BindingDB Entry DOI: 10.7270/Q2J105BG
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50218266 (CHEMBL303880) Show SMILES COc1cc2cnnc(Cc3c(Cl)cncc3Cl)c2cc1OC1CCCC1 Show InChI InChI=1S/C20H19Cl2N3O2/c1-26-19-6-12-9-24-25-18(7-15-16(21)10-23-11-17(15)22)14(12)8-20(19)27-13-4-2-3-5-13/h6,8-11,13H,2-5,7H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description In vitro inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair