BDBM50218269 CHEMBL73640

SMILES: COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCOC1

InChI Key: InChIKey=CCNKVJUYQNQLPA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50218269 (CHEMBL73640) Show SMILES COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCOC1 Show InChI InChI=1S/C19H17Cl2N3O3/c1-25-18-3-2-12-14(19(18)27-11-4-5-26-10-11)7-23-24-17(12)6-13-15(20)8-22-9-16(13)21/h2-3,7-9,11H,4-6,10H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	286	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Inhibition of rolipram binding to PDE4 from human neutrophils				Bioorg Med Chem Lett 10: 2235-8 (2000) BindingDB Entry DOI: 10.7270/Q2J105BG
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50218269 (CHEMBL73640) Show SMILES COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCOC1 Show InChI InChI=1S/C19H17Cl2N3O3/c1-25-18-3-2-12-14(19(18)27-11-4-5-26-10-11)7-23-24-17(12)6-13-15(20)8-22-9-16(13)21/h2-3,7-9,11H,4-6,10H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 4 from human neutrophils				Bioorg Med Chem Lett 10: 2235-8 (2000) BindingDB Entry DOI: 10.7270/Q2J105BG
					More data for this Ligand-Target Pair