BDBM50218281 5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)-1-pivaloylpyrrolidin-3-yl)thiophene-2-carboxamide::CHEMBL238356

SMILES: CC(C)(C)C(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=VCFNNCKDEFBCPC-RBUKOAKNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218281 (5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...) Show SMILES CC(C)(C)C(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O Show InChI InChI=1S/C26H27ClN4O4S/c1-26(2,3)25(35)30-14-18(19(15-30)29-24(34)20-11-12-21(27)36-20)28-23(33)16-7-9-17(10-8-16)31-13-5-4-6-22(31)32/h4-13,18-19H,14-15H2,1-3H3,(H,28,33)(H,29,34)/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair