BDBM50218284 5-chloro-N-((1R,2S,4S)-4-(cyclopropylcarbamoyl)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL401444

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1C[C@H](C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)NC1CC1

InChI Key: InChIKey=DBBUIBYPRPEIJE-FFZOFVMBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218284 (5-chloro-N-((1R,2S,4S)-4-(cyclopropylcarbamoyl)-2-...) Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1C[C@H](C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)NC1CC1 Show InChI InChI=1S/C26H25ClN4O4S/c27-22-11-10-21(36-22)26(35)30-20-14-16(25(34)28-17-6-7-17)13-19(20)29-24(33)15-4-8-18(9-5-15)31-12-2-1-3-23(31)32/h1-5,8-12,16-17,19-20H,6-7,13-14H2,(H,28,34)(H,29,33)(H,30,35)/t16-,19-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair