new BindingDB logo
myBDB logout

BDBM50218284 5-chloro-N-((1R,2S,4S)-4-(cyclopropylcarbamoyl)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL401444

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1C[C@H](C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)NC1CC1

InChI Key: InChIKey=DBBUIBYPRPEIJE-FFZOFVMBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218284   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50218284
PNG
(5-chloro-N-((1R,2S,4S)-4-(cyclopropylcarbamoyl)-2-...)
Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1C[C@H](C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)NC1CC1
Show InChI InChI=1S/C26H25ClN4O4S/c27-22-11-10-21(36-22)26(35)30-20-14-16(25(34)28-17-6-7-17)13-19(20)29-24(33)15-4-8-18(9-5-15)31-12-2-1-3-23(31)32/h1-5,8-12,16-17,19-20H,6-7,13-14H2,(H,28,34)(H,29,33)(H,30,35)/t16-,19-,20+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 5041-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.020
BindingDB Entry DOI: 10.7270/Q23J3CPQ
More data for this
Ligand-Target Pair