BDBM50218286 (3R,4S)-3-(2-chlorothiophene-5-carboxamido)-N-methyl-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidine-1-carboxamide::CHEMBL392508

SMILES: CNC(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=WDGSIXLLWZZNKD-DLBZAZTESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218286 ((3R,4S)-3-(2-chlorothiophene-5-carboxamido)-N-meth...) Show SMILES CNC(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O Show InChI InChI=1S/C23H22ClN5O4S/c1-25-23(33)28-12-16(17(13-28)27-22(32)18-9-10-19(24)34-18)26-21(31)14-5-7-15(8-6-14)29-11-3-2-4-20(29)30/h2-11,16-17H,12-13H2,1H3,(H,25,33)(H,26,31)(H,27,32)/t16-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair