BDBM50218300 (3R,4S)-3-(2-chlorothiophene-5-carboxamido)-N,N-dimethyl-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidine-1-carboxamide::CHEMBL236021

SMILES: CN(C)C(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=FXDVAQXZLKXSAC-ZWKOTPCHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218300 ((3R,4S)-3-(2-chlorothiophene-5-carboxamido)-N,N-di...) Show SMILES CN(C)C(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O Show InChI InChI=1S/C24H24ClN5O4S/c1-28(2)24(34)29-13-17(18(14-29)27-23(33)19-10-11-20(25)35-19)26-22(32)15-6-8-16(9-7-15)30-12-4-3-5-21(30)31/h3-12,17-18H,13-14H2,1-2H3,(H,26,32)(H,27,33)/t17-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair