new BindingDB logo
myBDB logout

BDBM50218301 3-chloro-N-((1S,2R)-1-(4-(2-oxopyridin-1(2H)-yl)benzamido)-2,3-dihydro-1H-inden-2-yl)-1H-indole-6-carboxamide::CHEMBL236643

SMILES: Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1Cc2ccccc2[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=ADBZQJUYCOQPFF-IAPPQJPRSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218301   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50218301
PNG
(3-chloro-N-((1S,2R)-1-(4-(2-oxopyridin-1(2H)-yl)be...)
Show SMILES Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1Cc2ccccc2[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O
Show InChI InChI=1S/C30H23ClN4O3/c31-24-17-32-25-16-20(10-13-23(24)25)30(38)33-26-15-19-5-1-2-6-22(19)28(26)34-29(37)18-8-11-21(12-9-18)35-14-4-3-7-27(35)36/h1-14,16-17,26,28,32H,15H2,(H,33,38)(H,34,37)/t26-,28+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 5041-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.020
BindingDB Entry DOI: 10.7270/Q23J3CPQ
More data for this
Ligand-Target Pair