BDBM50218302 CHEMBL445941::N-((1R,2S,4S)-4-((2-methoxyethyl)carbamoyl)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)-5-chlorothiophene-2-carboxamide

SMILES: COCCNC(=O)[C@@H]1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=FOTAAGYZMUUXRR-YSIASYRMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218302 (CHEMBL445941 | N-((1R,2S,4S)-4-((2-methoxyethyl)ca...) Show SMILES COCCNC(=O)[C@@H]1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O Show InChI InChI=1S/C26H27ClN4O5S/c1-36-13-11-28-24(33)17-14-19(20(15-17)30-26(35)21-9-10-22(27)37-21)29-25(34)16-5-7-18(8-6-16)31-12-3-2-4-23(31)32/h2-10,12,17,19-20H,11,13-15H2,1H3,(H,28,33)(H,29,34)(H,30,35)/t17-,19-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair