BDBM50218303 5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)-2,3-dihydro-1H-inden-1-yl)thiophene-2-carboxamide::CHEMBL236440
SMILES: Clc1ccc(s1)C(=O)N[C@H]1[C@H](Cc2ccccc12)NC(=O)c1ccc(cc1)-n1ccccc1=O
InChI Key: InChIKey=OGJPWEIXFUNYHQ-GBXCKJPGSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Homo sapiens (Human)) | BDBM50218303 (5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company Curated by ChEMBL | Assay Description Inhibition of human factor 10a | Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ | |||||||||||
More data for this Ligand-Target Pair |