BDBM50218311 (3R,4S)-(9H-fluoren-9-yl)methyl 3-(2-chlorothiophene-5-carboxamido)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidine-1-carboxylate::CHEMBL392005

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1CN(C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)OCC1c2ccccc2-c2ccccc12

InChI Key: InChIKey=AMFXTZGKJYXSPI-XZWHSSHBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218311 ((3R,4S)-(9H-fluoren-9-yl)methyl 3-(2-chlorothiophe...) Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1CN(C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)OCC1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C36H29ClN4O5S/c37-32-17-16-31(47-32)35(44)39-30-20-40(36(45)46-21-28-26-9-3-1-7-24(26)25-8-2-4-10-27(25)28)19-29(30)38-34(43)22-12-14-23(15-13-22)41-18-6-5-11-33(41)42/h1-18,28-30H,19-21H2,(H,38,43)(H,39,44)/t29-,30+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair