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BDBM50218314 5-chloro-N-((1R,2S,4S)-4-(morpholine-4-carbonyl)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL538905

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1C[C@H](C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)N1CCOCC1

InChI Key: InChIKey=KIRAXNSWURSOKF-SESVDKBCSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218314   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50218314
PNG
(5-chloro-N-((1R,2S,4S)-4-(morpholine-4-carbonyl)-2...)
Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1C[C@H](C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)N1CCOCC1
Show InChI InChI=1S/C27H27ClN4O5S/c28-23-9-8-22(38-23)26(35)30-21-16-18(27(36)31-11-13-37-14-12-31)15-20(21)29-25(34)17-4-6-19(7-5-17)32-10-2-1-3-24(32)33/h1-10,18,20-21H,11-16H2,(H,29,34)(H,30,35)/t18-,20-,21+/m0/s1
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Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 5041-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.020
BindingDB Entry DOI: 10.7270/Q23J3CPQ
More data for this
Ligand-Target Pair