BDBM50218317 (3R,4S)-ethyl 3-(3-chloro-1H-indole-6-carboxamido)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidine-1-carboxylate::CHEMBL238148

SMILES: CCOC(=O)N1C[C@H](NC(=O)c2ccc(cc2)-n2ccccc2=O)[C@@H](C1)NC(=O)c1ccc2c(Cl)c[nH]c2c1

InChI Key: InChIKey=TYMLQLUKAZIRAK-BJKOFHAPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50218317 ((3R,4S)-ethyl 3-(3-chloro-1H-indole-6-carboxamido)...) Show SMILES CCOC(=O)N1C[C@H](NC(=O)c2ccc(cc2)-n2ccccc2=O)[C@@H](C1)NC(=O)c1ccc2c(Cl)c[nH]c2c1 Show InChI InChI=1S/C28H26ClN5O5/c1-2-39-28(38)33-15-23(24(16-33)32-27(37)18-8-11-20-21(29)14-30-22(20)13-18)31-26(36)17-6-9-19(10-7-17)34-12-4-3-5-25(34)35/h3-14,23-24,30H,2,15-16H2,1H3,(H,31,36)(H,32,37)/t23-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 5041-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.020 BindingDB Entry DOI: 10.7270/Q23J3CPQ
					More data for this Ligand-Target Pair