null

SMILES: O=C(N[C@@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=DIYWXMAFIJZOJZ-LOIQHOORSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50218388 (CHEMBL78986) Show SMILES O=C(N[C@@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H32N2O/c26-22(23-13-18-10-19(14-23)12-20(11-18)15-23)24-21-7-9-25(16-21)8-6-17-4-2-1-3-5-17/h1-5,18-21H,6-16H2,(H,24,26)/t18?,19?,20?,21-,23?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50218388 (CHEMBL78986) Show SMILES O=C(N[C@@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H32N2O/c26-22(23-13-18-10-19(14-23)12-20(11-18)15-23)24-21-7-9-25(16-21)8-6-17-4-2-1-3-5-17/h1-5,18-21H,6-16H2,(H,24,26)/t18?,19?,20?,21-,23?/m1/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptor				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50218388 (CHEMBL78986) Show SMILES O=C(N[C@@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H32N2O/c26-22(23-13-18-10-19(14-23)12-20(11-18)15-23)24-21-7-9-25(16-21)8-6-17-4-2-1-3-5-17/h1-5,18-21H,6-16H2,(H,24,26)/t18?,19?,20?,21-,23?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair