null

SMILES: CN1c2ccc(NS(=O)(=O)c3cccc(F)c3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C

InChI Key: InChIKey=JPJVQVRLRJICIF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218482 (4-[2-(3-fluoro-benzenesulfonylamino)-5,7,7,10,10-p...) Show SMILES CN1c2ccc(NS(=O)(=O)c3cccc(F)c3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C |t:21| Show InChI InChI=1S/C35H34FN3O4S/c1-34(2)15-16-35(3,4)28-20-31-26(19-27(28)34)32(21-9-11-22(12-10-21)33(40)41)37-29-18-24(13-14-30(29)39(31)5)38-44(42,43)25-8-6-7-23(36)17-25/h6-14,17-20,38H,15-16H2,1-5H3,(H,40,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of 9-cis-retinoic acid-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218482 (4-[2-(3-fluoro-benzenesulfonylamino)-5,7,7,10,10-p...) Show SMILES CN1c2ccc(NS(=O)(=O)c3cccc(F)c3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C |t:21| Show InChI InChI=1S/C35H34FN3O4S/c1-34(2)15-16-35(3,4)28-20-31-26(19-27(28)34)32(21-9-11-22(12-10-21)33(40)41)37-29-18-24(13-14-30(29)39(31)5)38-44(42,43)25-8-6-7-23(36)17-25/h6-14,17-20,38H,15-16H2,1-5H3,(H,40,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of LG100268-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair