null

SMILES: CN1c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C

InChI Key: InChIKey=FIHASMHGRHRIGK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218483 (4-[5,7,7,10,10-pentamethyl-2-(naphthalene-1-sulfon...) Show SMILES CN1c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C |t:25| Show InChI InChI=1S/C39H37N3O4S/c1-38(2)19-20-39(3,4)31-23-34-29(22-30(31)38)36(25-13-15-26(16-14-25)37(43)44)40-32-21-27(17-18-33(32)42(34)5)41-47(45,46)35-12-8-10-24-9-6-7-11-28(24)35/h6-18,21-23,41H,19-20H2,1-5H3,(H,43,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of LG100268-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218483 (4-[5,7,7,10,10-pentamethyl-2-(naphthalene-1-sulfon...) Show SMILES CN1c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C |t:25| Show InChI InChI=1S/C39H37N3O4S/c1-38(2)19-20-39(3,4)31-23-34-29(22-30(31)38)36(25-13-15-26(16-14-25)37(43)44)40-32-21-27(17-18-33(32)42(34)5)41-47(45,46)35-12-8-10-24-9-6-7-11-28(24)35/h6-18,21-23,41H,19-20H2,1-5H3,(H,43,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of 9-cis-retinoic acid-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair