null

SMILES: CN1c2ccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C

InChI Key: InChIKey=ZUZYTZXAGUZPBP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218501   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218501 (4-[2-(biphenyl-4-sulfonylamino)-5,7,7,10,10-pentam...) Show SMILES CN1c2ccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C |t:27| Show InChI InChI=1S/C41H39N3O4S/c1-40(2)21-22-41(3,4)34-25-37-32(24-33(34)40)38(28-11-13-29(14-12-28)39(45)46)42-35-23-30(17-20-36(35)44(37)5)43-49(47,48)31-18-15-27(16-19-31)26-9-7-6-8-10-26/h6-20,23-25,43H,21-22H2,1-5H3,(H,45,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of LG100268-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218501 (4-[2-(biphenyl-4-sulfonylamino)-5,7,7,10,10-pentam...) Show SMILES CN1c2ccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C |t:27| Show InChI InChI=1S/C41H39N3O4S/c1-40(2)21-22-41(3,4)34-25-37-32(24-33(34)40)38(28-11-13-29(14-12-28)39(45)46)42-35-23-30(17-20-36(35)44(37)5)43-49(47,48)31-18-15-27(16-19-31)26-9-7-6-8-10-26/h6-20,23-25,43H,21-22H2,1-5H3,(H,45,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of 9-cis-retinoic acid-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair