BDBM50218559 CHEMBL64993

SMILES: CC1OC(Oc2c(O)c3C(=O)c4ccccc4C(=O)c3c3cccnc23)C(F)C(O)C1O

InChI Key: InChIKey=WPZUNLCLZODAEV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase II (Homo sapiens (Human))	BDBM50218559 (CHEMBL64993) Show SMILES CC1OC(Oc2c(O)c3C(=O)c4ccccc4C(=O)c3c3cccnc23)C(F)C(O)C1O Show InChI InChI=1S/C23H18FNO7/c1-9-17(26)21(30)15(24)23(31-9)32-22-16-12(7-4-8-25-16)13-14(20(22)29)19(28)11-6-3-2-5-10(11)18(13)27/h2-9,15,17,21,23,26,29-30H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bioorganic Chemistry Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against topoisomerase II				Bioorg Med Chem Lett 10: 203-7 (2000) BindingDB Entry DOI: 10.7270/Q2W66NX0
					More data for this Ligand-Target Pair