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BDBM50218681 CHEMBL98091

SMILES: CCCc1nc(Nc2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12

InChI Key: InChIKey=UIVDXALOJZCZHG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218681   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50218681
PNG
(CHEMBL98091)
Show SMILES CCCc1nc(Nc2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12
Show InChI InChI=1S/C19H23Cl2N5/c1-4-7-16-17-18(25(5-2)6-3)22-10-11-26(17)19(24-16)23-15-9-8-13(20)12-14(15)21/h8-12H,4-7H2,1-3H3,(H,23,24)
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PubMed
 825n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.

Bioorg Med Chem Lett 12: 291-4 (2002)


BindingDB Entry DOI: 10.7270/Q22N54H2
More data for this
Ligand-Target Pair