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BDBM50218684 CHEMBL99741

SMILES: CCCN(CCC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CC)c12

InChI Key: InChIKey=ZEKCABDGNPZNKX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218684   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50218684
PNG
(CHEMBL99741)
Show SMILES CCCN(CCC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CC)c12
Show InChI InChI=1S/C20H25Cl2N5/c1-4-10-26(11-5-2)19-18-16(6-3)24-20(27(18)12-9-23-19)25-17-8-7-14(21)13-15(17)22/h7-9,12-13H,4-6,10-11H2,1-3H3,(H,24,25)
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 223n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.

Bioorg Med Chem Lett 12: 291-4 (2002)


BindingDB Entry DOI: 10.7270/Q22N54H2
More data for this
Ligand-Target Pair