BDBM50218753 CHEMBL101093
SMILES: CCCN(CCC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CCC)c12
InChI Key: InChIKey=DCBJJSIOAORGBH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin-releasing factor receptor 1/2 (Rattus norvegicus (rat)-RAT) | BDBM50218753 (CHEMBL101093) | PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 492 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement. | Bioorg Med Chem Lett 12: 291-4 (2002) BindingDB Entry DOI: 10.7270/Q22N54H2 | |||||||||||
More data for this Ligand-Target Pair |