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BDBM50218754 CHEMBL101574

SMILES: CCCN(CCC)c1nccn2c(Nc3c(C)cc(C)cc3C)nc(CC)c12

InChI Key: InChIKey=OZLYWCKBSGBPGS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218754   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50218754
PNG
(CHEMBL101574)
Show SMILES CCCN(CCC)c1nccn2c(Nc3c(C)cc(C)cc3C)nc(CC)c12
Show InChI InChI=1S/C23H33N5/c1-7-11-27(12-8-2)22-21-19(9-3)25-23(28(21)13-10-24-22)26-20-17(5)14-16(4)15-18(20)6/h10,13-15H,7-9,11-12H2,1-6H3,(H,25,26)
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PubMed
 173n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.

Bioorg Med Chem Lett 12: 291-4 (2002)


BindingDB Entry DOI: 10.7270/Q22N54H2
More data for this
Ligand-Target Pair