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BDBM50218783 CHEMBL308610

SMILES: C=CCc1c(OCc2ccccc2)ccc2ccc(=O)oc12

InChI Key: InChIKey=STKHKNPMRPNLCA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218783   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Steroid 5-alpha-reductase


(Homo sapiens (Human))		BDBM50218783
PNG
(CHEMBL308610)
Show SMILES C=CCc1c(OCc2ccccc2)ccc2ccc(=O)oc12
Show InChI InChI=1S/C19H16O3/c1-2-6-16-17(21-13-14-7-4-3-5-8-14)11-9-15-10-12-18(20)22-19(15)16/h2-5,7-12H,1,6,13H2
UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>4n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)

Bioorg Med Chem Lett 11: 2361-3 (2001)


BindingDB Entry DOI: 10.7270/Q2RR1ZS9
More data for this
Ligand-Target Pair