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BDBM50218788 CHEMBL77649

SMILES: CC(C)(Oc1ccc2ccc(=O)oc2c1)C#C

InChI Key: InChIKey=BHDRZDUUHXZZPQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Steroid 5-alpha-reductase


(Homo sapiens (Human))		BDBM50218788
PNG
(CHEMBL77649)
Show SMILES CC(C)(Oc1ccc2ccc(=O)oc2c1)C#C
Show InChI InChI=1S/C14H12O3/c1-4-14(2,3)17-11-7-5-10-6-8-13(15)16-12(10)9-11/h1,5-9H,2-3H3
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PubMed
n/an/a>20n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)

Bioorg Med Chem Lett 11: 2361-3 (2001)


BindingDB Entry DOI: 10.7270/Q2RR1ZS9
More data for this
Ligand-Target Pair