BDBM50219029 CHEMBL390679::N-{3-[1-(2-diphenylacetylamino-ethyl)-piperidin-4-yl]-phenyl-isobutyramide

SMILES: CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1

InChI Key: InChIKey=VSKUPRJZZDVXEM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50219029 (CHEMBL390679 | N-{3-[1-(2-diphenylacetylamino-ethy...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
GPR24 (RAT)	BDBM50219029 (CHEMBL390679 | N-{3-[1-(2-diphenylacetylamino-ethy...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair