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BDBM50219051 CHEMBL245229::N-(3-{1-[4-(4-methoxyphenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide

SMILES: COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1

InChI Key: InChIKey=RBVKMXSYCQGAEL-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219051   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR24


(RAT)
BDBM50219051
PNG
(CHEMBL245229 | N-(3-{1-[4-(4-methoxyphenoxy)benzyl...)
Show SMILES COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1
Show InChI InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-6-4-5-24(19-25)23-15-17-31(18-16-23)20-22-7-9-27(10-8-22)34-28-13-11-26(33-3)12-14-28/h4-14,19,21,23H,15-18,20H2,1-3H3,(H,30,32)
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CHEMBL
PC cid
PC sid
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Article
PubMed
35n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50219051
PNG
(CHEMBL245229 | N-(3-{1-[4-(4-methoxyphenoxy)benzyl...)
Show SMILES COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1
Show InChI InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-6-4-5-24(19-25)23-15-17-31(18-16-23)20-22-7-9-27(10-8-22)34-28-13-11-26(33-3)12-14-28/h4-14,19,21,23H,15-18,20H2,1-3H3,(H,30,32)
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UniProtKB/SwissProt

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antibodypedia
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CHEMBL
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PC sid
UniChem

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Article
PubMed
1.40E+3n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human recombinant dopamine D2 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219051
PNG
(CHEMBL245229 | N-(3-{1-[4-(4-methoxyphenoxy)benzyl...)
Show SMILES COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1
Show InChI InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-6-4-5-24(19-25)23-15-17-31(18-16-23)20-22-7-9-27(10-8-22)34-28-13-11-26(33-3)12-14-28/h4-14,19,21,23H,15-18,20H2,1-3H3,(H,30,32)
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KEGG

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 720n/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assay


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair