BDBM50219137 7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-3-ol::7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecin-3-ol::CHEMBL231070

SMILES: CN1CCCc2ccccc2Cc2ccc(O)cc2CC1

InChI Key: InChIKey=HWJXQZBZKJYOMP-UHFFFAOYSA-N

Data: 7 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50219137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D1 receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human dopamine D1 receptor				J Med Chem 50: 4528-33 (2007) Article DOI: 10.1021/jm070388+ BindingDB Entry DOI: 10.7270/Q2S46RPG
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human dopamine D5 receptor expressed in HEK293 cells				J Med Chem 50: 4528-33 (2007) Article DOI: 10.1021/jm070388+ BindingDB Entry DOI: 10.7270/Q2S46RPG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D2L receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D4.4 receptor expressed in CHO cells				J Med Chem 50: 4528-33 (2007) Article DOI: 10.1021/jm070388+ BindingDB Entry DOI: 10.7270/Q2S46RPG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in HEK293 cells				J Med Chem 50: 4528-33 (2007) Article DOI: 10.1021/jm070388+ BindingDB Entry DOI: 10.7270/Q2S46RPG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 50: 4528-33 (2007) Article DOI: 10.1021/jm070388+ BindingDB Entry DOI: 10.7270/Q2S46RPG
					More data for this Ligand-Target Pair
5-HT2 (PIG)	BDBM50219137 (7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...) Show SMILES CN1CCCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI InChI=1S/C19H23NO/c1-20-11-4-7-15-5-2-3-6-16(15)13-17-8-9-19(21)14-18(17)10-12-20/h2-3,5-6,8-9,14,21H,4,7,10-13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.14	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Antagonist activity at serotonin 5HT2A receptor assessed as effect on 5HT-induced isometric contractile force in isolated rings of pig coronary arter...				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair