BDBM50219408 CHEMBL84115

SMILES: COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(C)=O

InChI Key: InChIKey=WGUXBENBNHCCQX-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50219408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219408 (CHEMBL84115) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(C)=O |c:16| Show InChI InChI=1S/C17H15Cl2N3O2/c1-10(23)22-9-11-5-12(24-2)3-4-13(11)17(21-22)6-14-15(18)7-20-8-16(14)19/h3-5,7-8H,6,9H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	397	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 12: 5-8 (2002) BindingDB Entry DOI: 10.7270/Q2SB47Z5
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219408 (CHEMBL84115) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(C)=O |c:16| Show InChI InChI=1S/C17H15Cl2N3O2/c1-10(23)22-9-11-5-12(24-2)3-4-13(11)17(21-22)6-14-15(18)7-20-8-16(14)19/h3-5,7-8H,6,9H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Inhibition of human neutrophil phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 12: 5-8 (2002) BindingDB Entry DOI: 10.7270/Q2SB47Z5
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219408 (CHEMBL84115) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(C)=O |c:16| Show InChI InChI=1S/C17H15Cl2N3O2/c1-10(23)22-9-11-5-12(24-2)3-4-13(11)17(21-22)6-14-15(18)7-20-8-16(14)19/h3-5,7-8H,6,9H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219408 (CHEMBL84115) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(C)=O |c:16| Show InChI InChI=1S/C17H15Cl2N3O2/c1-10(23)22-9-11-5-12(24-2)3-4-13(11)17(21-22)6-14-15(18)7-20-8-16(14)19/h3-5,7-8H,6,9H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description In vitro inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair