Found 4 hits for monomerid = 50219411 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219411
(CHEMBL82934)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4) |
Bioorg Med Chem Lett 12: 5-8 (2002)
BindingDB Entry DOI: 10.7270/Q2SB47Z5 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219411
(CHEMBL82934)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description Inhibition of human neutrophil phosphodiesterase type IV (PDE4) |
Bioorg Med Chem Lett 12: 5-8 (2002)
BindingDB Entry DOI: 10.7270/Q2SB47Z5 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219411
(CHEMBL82934)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description Inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219411
(CHEMBL82934)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this Ligand-Target Pair | |