BDBM50219411 CHEMBL82934

SMILES: COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O

InChI Key: InChIKey=MAXOLFIODKJKGF-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50219411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219411 (CHEMBL82934) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 12: 5-8 (2002) BindingDB Entry DOI: 10.7270/Q2SB47Z5
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219411 (CHEMBL82934) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Inhibition of human neutrophil phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 12: 5-8 (2002) BindingDB Entry DOI: 10.7270/Q2SB47Z5
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219411 (CHEMBL82934) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50219411 (CHEMBL82934) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(N)=O |c:16| Show InChI InChI=1S/C16H14Cl2N4O2/c1-24-10-2-3-11-9(4-10)8-22(16(19)23)21-15(11)5-12-13(17)6-20-7-14(12)18/h2-4,6-7H,5,8H2,1H3,(H2,19,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description In vitro inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair