Found 4 hits for monomerid = 50219417 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219417
(CHEMBL421343)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1OC1CCCC1)C(C)=O |c:16| Show InChI InChI=1S/C22H23Cl2N3O3/c1-13(28)27-12-17-15(20(26-27)9-16-18(23)10-25-11-19(16)24)7-8-21(29-2)22(17)30-14-5-3-4-6-14/h7-8,10-11,14H,3-6,9,12H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 128 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4) |
Bioorg Med Chem Lett 12: 5-8 (2002)
BindingDB Entry DOI: 10.7270/Q2SB47Z5 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219417
(CHEMBL421343)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1OC1CCCC1)C(C)=O |c:16| Show InChI InChI=1S/C22H23Cl2N3O3/c1-13(28)27-12-17-15(20(26-27)9-16-18(23)10-25-11-19(16)24)7-8-21(29-2)22(17)30-14-5-3-4-6-14/h7-8,10-11,14H,3-6,9,12H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description Inhibition of human neutrophil phosphodiesterase type IV (PDE4) |
Bioorg Med Chem Lett 12: 5-8 (2002)
BindingDB Entry DOI: 10.7270/Q2SB47Z5 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219417
(CHEMBL421343)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1OC1CCCC1)C(C)=O |c:16| Show InChI InChI=1S/C22H23Cl2N3O3/c1-13(28)27-12-17-15(20(26-27)9-16-18(23)10-25-11-19(16)24)7-8-21(29-2)22(17)30-14-5-3-4-6-14/h7-8,10-11,14H,3-6,9,12H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description Inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM50219417
(CHEMBL421343)Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1OC1CCCC1)C(C)=O |c:16| Show InChI InChI=1S/C22H23Cl2N3O3/c1-13(28)27-12-17-15(20(26-27)9-16-18(23)10-25-11-19(16)24)7-8-21(29-2)22(17)30-14-5-3-4-6-14/h7-8,10-11,14H,3-6,9,12H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description In vitro inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this Ligand-Target Pair | |