BDBM50219476 2-(3-chlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL391076

SMILES: COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1)C(F)(F)F

InChI Key: InChIKey=PNAJZOSKCGZBFF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50219476 (2-(3-chlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro-2-m...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1)C(F)(F)F |w:13.14| Show InChI InChI=1S/C20H21ClF4O2/c1-18(2,16-10-15(22)7-8-17(16)27-3)12-19(26,20(23,24)25)11-13-5-4-6-14(21)9-13/h4-10,26H,11-12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cell				Bioorg Med Chem Lett 17: 5025-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50219476 (2-(3-chlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro-2-m...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1)C(F)(F)F |w:13.14| Show InChI InChI=1S/C20H21ClF4O2/c1-18(2,16-10-15(22)7-8-17(16)27-3)12-19(26,20(23,24)25)11-13-5-4-6-14(21)9-13/h4-10,26H,11-12H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cell				Bioorg Med Chem Lett 17: 5025-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50219476 (2-(3-chlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro-2-m...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1)C(F)(F)F |w:13.14| Show InChI InChI=1S/C20H21ClF4O2/c1-18(2,16-10-15(22)7-8-17(16)27-3)12-19(26,20(23,24)25)11-13-5-4-6-14(21)9-13/h4-10,26H,11-12H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cell				Bioorg Med Chem Lett 17: 5025-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2
					More data for this Ligand-Target Pair