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BDBM50219958 CHEMBL23112

SMILES: CCC(CCOC)n1c(nc2c(ccnc12)-c1ccc(cc1Cl)C(F)(F)F)C1CC1

InChI Key: InChIKey=VBWGHTWPMPCHNN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219958   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50219958
PNG
(CHEMBL23112)
Show SMILES CCC(CCOC)n1c(nc2c(ccnc12)-c1ccc(cc1Cl)C(F)(F)F)C1CC1
Show InChI InChI=1S/C22H23ClF3N3O/c1-3-15(9-11-30-2)29-20(13-4-5-13)28-19-17(8-10-27-21(19)29)16-7-6-14(12-18(16)23)22(24,25)26/h6-8,10,12-13,15H,3-5,9,11H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars
PubMed
 21n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
In vitro binding affinity to the CRF receptor in rat cortical homogenates

Bioorg Med Chem Lett 13: 125-8 (2003)


BindingDB Entry DOI: 10.7270/Q2JM2CV9
More data for this
Ligand-Target Pair