BindingDB logo
myBDB logout

BDBM50219964 CHEMBL23105

SMILES: CCc1nc2c(ccnc2n1C(CCOC)C1CCC1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=RZHRWWAIUQTLEF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219964   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50219964
PNG
(CHEMBL23105)
Show SMILES CCc1nc2c(ccnc2n1C(CCOC)C1CCC1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H25Cl2N3O/c1-3-20-26-21-17(16-8-7-15(23)13-18(16)24)9-11-25-22(21)27(20)19(10-12-28-2)14-5-4-6-14/h7-9,11,13-14,19H,3-6,10,12H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 2.40n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
In vitro binding affinity to the CRF receptor in rat cortical homogenates

Bioorg Med Chem Lett 13: 125-8 (2003)


BindingDB Entry DOI: 10.7270/Q2JM2CV9
More data for this
Ligand-Target Pair