BDBM50220087 2-(3,5-dichlorophenyl)-7-methylpyrido[2,3-d]pyrimidine::CHEMBL239622

SMILES: Cc1ccc2cnc(nc2n1)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=FLUVRVSFPUILNW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50220087 (2-(3,5-dichlorophenyl)-7-methylpyrido[2,3-d]pyrimi...) Show SMILES Cc1ccc2cnc(nc2n1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H9Cl2N3/c1-8-2-3-9-7-17-13(19-14(9)18-8)10-4-11(15)6-12(16)5-10/h2-7H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technology				Bioorg Med Chem Lett 17: 5396-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.047 BindingDB Entry DOI: 10.7270/Q2JH3KWK
					More data for this Ligand-Target Pair