BDBM50220179 CHEMBL243906::N-{4'-[(trifluoromethyl)sulfonyl]-4-biphenylyl}methanesulfonamide

SMILES: CS(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)C(F)(F)F

InChI Key: InChIKey=VRUUANRIDBVMSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50220179 (CHEMBL243906 | N-{4'-[(trifluoromethyl)sulfonyl]-4...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)C(F)(F)F Show InChI InChI=1S/C14H12F3NO4S2/c1-23(19,20)18-12-6-2-10(3-7-12)11-4-8-13(9-5-11)24(21,22)14(15,16)17/h2-9,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair