BDBM50220197 CHEMBL242357::N-[3-methyl-4'-(trifluoromethyl)-4-biphenylyl]sulfamide

SMILES: Cc1cc(ccc1NS(N)(=O)=O)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=NPVURYICSQTIHF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50220197 (CHEMBL242357 | N-[3-methyl-4'-(trifluoromethyl)-4-...) Show SMILES Cc1cc(ccc1NS(N)(=O)=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O2S/c1-9-8-11(4-7-13(9)19-22(18,20)21)10-2-5-12(6-3-10)14(15,16)17/h2-8,19H,1H3,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair