BDBM50220330 (S)-1-(3-(2,5-difluorophenyl)-5-(3-(dimethylamino)propyl)-5-phenyl-4,5-dihydropyrazol-1-yl)ethanone::CHEMBL392148

SMILES: CN(C)CCC[C@]1(CC(=NN1C(C)=O)c1cc(F)ccc1F)c1ccccc1

InChI Key: InChIKey=SARDOHYMRJFBKL-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50220330 ((S)-1-(3-(2,5-difluorophenyl)-5-(3-(dimethylamino)...) Show SMILES CN(C)CCC[C@]1(CC(=NN1C(C)=O)c1cc(F)ccc1F)c1ccccc1 |c:8| Show InChI InChI=1S/C22H25F2N3O/c1-16(28)27-22(12-7-13-26(2)3,17-8-5-4-6-9-17)15-21(25-27)19-14-18(23)10-11-20(19)24/h4-6,8-11,14H,7,12-13,15H2,1-3H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of KSP by ATPase assay				Bioorg Med Chem Lett 17: 5390-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.046 BindingDB Entry DOI: 10.7270/Q2RX9BSM
					More data for this Ligand-Target Pair