null
SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cccc(OCCN)c2)c2ccccc12
InChI Key: InChIKey=SBZRRXHZTHRZPW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50220370 (3-(1-methylindol-3-yl)-4-[3-(2-aminoethoxy)phenyl]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
CrystalGenomics, Inc. Curated by ChEMBL | Assay Description Inhibition of GSK3beta at 5 uM | Bioorg Med Chem Lett 17: 5686-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.056 BindingDB Entry DOI: 10.7270/Q2HH6JT3 | |||||||||||
More data for this Ligand-Target Pair |