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BDBM50220371 2-(2,4-dichlorophenyl)-7-hydroxy-N-phenethyl-1H-benzo[d]imidazole-4-carboxamide::CHEMBL400745

SMILES: Oc1ccc(C(=O)NCCc2ccccc2)c2[nH]c(nc12)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=XUPWWSYXJNCEDU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220371   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50220371
PNG
(2-(2,4-dichlorophenyl)-7-hydroxy-N-phenethyl-1H-be...)
Show SMILES Oc1ccc(C(=O)NCCc2ccccc2)c2[nH]c(nc12)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H17Cl2N3O2/c23-14-6-7-15(17(24)12-14)21-26-19-16(8-9-18(28)20(19)27-21)22(29)25-11-10-13-4-2-1-3-5-13/h1-9,12,28H,10-11H2,(H,25,29)(H,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



CrystalGenomics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of GSK3beta at 5 uM


Bioorg Med Chem Lett 17: 5686-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.056
BindingDB Entry DOI: 10.7270/Q2HH6JT3
More data for this
Ligand-Target Pair