BDBM50220379 3,2'-bis-trifluoromethyl-biphenyl-4-carbonitrile::CHEMBL396656

SMILES: FC(F)(F)c1cc(ccc1C#N)-c1ccccc1C(F)(F)F

InChI Key: InChIKey=LVFYAAITUNIVMI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50220379 (3,2'-bis-trifluoromethyl-biphenyl-4-carbonitrile |...) Show SMILES FC(F)(F)c1cc(ccc1C#N)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H7F6N/c16-14(17,18)12-4-2-1-3-11(12)9-5-6-10(8-22)13(7-9)15(19,20)21/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cells				Bioorg Med Chem Lett 17: 5529-32 (2007) Article DOI: 10.1016/j.bmcl.2007.08.034 BindingDB Entry DOI: 10.7270/Q2CR5T3S
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50220379 (3,2'-bis-trifluoromethyl-biphenyl-4-carbonitrile |...) Show SMILES FC(F)(F)c1cc(ccc1C#N)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H7F6N/c16-14(17,18)12-4-2-1-3-11(12)9-5-6-10(8-22)13(7-9)15(19,20)21/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assay				Bioorg Med Chem Lett 17: 5529-32 (2007) Article DOI: 10.1016/j.bmcl.2007.08.034 BindingDB Entry DOI: 10.7270/Q2CR5T3S
					More data for this Ligand-Target Pair