null

SMILES: O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H]2CCCN2)cc1

InChI Key: InChIKey=JZOQPCYGADPKSS-HXUWFJFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50220442 (CHEMBL64461) Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H]2CCCN2)cc1 Show InChI InChI=1S/C22H31N3O3/c26-21(17-4-5-17)18-6-8-19(9-7-18)28-16-2-11-24-12-14-25(15-13-24)22(27)20-3-1-10-23-20/h6-9,17,20,23H,1-5,10-16H2/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Histamine H3 receptor of rat cortical membranes.				Bioorg Med Chem Lett 12: 2035-7 (2002) BindingDB Entry DOI: 10.7270/Q2RB75SX
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50220442 (CHEMBL64461) Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H]2CCCN2)cc1 Show InChI InChI=1S/C22H31N3O3/c26-21(17-4-5-17)18-6-8-19(9-7-18)28-16-2-11-24-12-14-25(15-13-24)22(27)20-3-1-10-23-20/h6-9,17,20,23H,1-5,10-16H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Histamine H1 receptor of human membranes.				Bioorg Med Chem Lett 12: 2035-7 (2002) BindingDB Entry DOI: 10.7270/Q2RB75SX
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50220442 (CHEMBL64461) Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H]2CCCN2)cc1 Show InChI InChI=1S/C22H31N3O3/c26-21(17-4-5-17)18-6-8-19(9-7-18)28-16-2-11-24-12-14-25(15-13-24)22(27)20-3-1-10-23-20/h6-9,17,20,23H,1-5,10-16H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Histamine H2 receptor from human membranes				Bioorg Med Chem Lett 12: 2035-7 (2002) BindingDB Entry DOI: 10.7270/Q2RB75SX
					More data for this Ligand-Target Pair