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BDBM50220482 CHEMBL23788

SMILES: CCCC(C)n1c(nc2c(ccnc12)-c1ccc(Cl)cc1Cl)C(F)F

InChI Key: InChIKey=CKPFFVJDVQGCAJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220482   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50220482
PNG
(CHEMBL23788)
Show SMILES CCCC(C)n1c(nc2c(ccnc12)-c1ccc(Cl)cc1Cl)C(F)F
Show InChI InChI=1S/C18H17Cl2F2N3/c1-3-4-10(2)25-17-15(24-18(25)16(21)22)13(7-8-23-17)12-6-5-11(19)9-14(12)20/h5-10,16H,3-4H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 16n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
In vitro binding affinity to the CRF receptor in rat cortical homogenates

Bioorg Med Chem Lett 13: 125-8 (2003)


BindingDB Entry DOI: 10.7270/Q2JM2CV9
More data for this
Ligand-Target Pair