BDBM50220483 CHEMBL22213

SMILES: CCc1nc2c(ncnc2n1C(C1CC1)C1CC1)-c1ccc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=SLKGNKHXSKUHFT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1/2 (Rattus norvegicus (rat)-RAT)	BDBM50220483 (CHEMBL22213) Show SMILES CCc1nc2c(ncnc2n1C(C1CC1)C1CC1)-c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C21H20ClF3N4/c1-2-16-28-18-17(14-8-7-13(9-15(14)22)21(23,24)25)26-10-27-20(18)29(16)19(11-3-4-11)12-5-6-12/h7-12,19H,2-6H2,1H3	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 129-31 (2003) BindingDB Entry DOI: 10.7270/Q2DZ0BGD
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1/2 (Rattus norvegicus (rat)-RAT)	BDBM50220483 (CHEMBL22213) Show SMILES CCc1nc2c(ncnc2n1C(C1CC1)C1CC1)-c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C21H20ClF3N4/c1-2-16-28-18-17(14-8-7-13(9-15(14)22)21(23,24)25)26-10-27-20(18)29(16)19(11-3-4-11)12-5-6-12/h7-12,19H,2-6H2,1H3	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) BindingDB Entry DOI: 10.7270/Q2JM2CV9
					More data for this Ligand-Target Pair